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5-aminosalicylates (5-ASA) and sulfasalazine: Although oral mesalamine is widely used in practice, the meta-analysis of three large trials with mesalamine has shown a statistically significant but non-clinically relevant difference compared with placebo [31]

KD also shows potential in the prevention and treatment of cardiovascular disease (76)

CRP is synthesized in smooth muscle cells of atherosclerotic lesions with active disease, foam cells, macrophages, lymphocytes, monocytes, and endothelial cells within the atherosclerotic plaque (166170)