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The team used methods that Daniell has refined to highly express the human version of IGF-1 in plant leaves and remove the antibiotic resistance gene that is used to select for plants growing the target protein, crucial steps to get a therapy ready for clinical use

When treated with ibuprofen male livers showed no change in CYP1A2 and elevated levels of CYP4A1 while female livers showed significantly elevated expression of CYP1A2 and lower expression of CYP4A1