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It is made at barrier sites and by immune cells that act early, before antibodies even show up

Judd LL, Akiskal HS, Schettler PJ, et al

With those caveats in mind, here's what the published data shows at each stage

Figure 3 ERO1A (endoplasmic reticulum oxidase) ERO1 is an essential oxidoreductase involved in disulfide formation of nascent proteins in the endoplasmic reticulum (ER)