Park, A.R
Disclosures: Kathryn del Valle: Nothing to Disclose, Dana Kay: Nothing to Disclose, Michael Krowka: Nothing to Disclose, James Runo: Nothing to Disclose, Corey Sadd: Nothing to Disclose, Julie Heimbach: Nothing to Disclose, Rodrigo Cartin-Ceba: Nothing to Disclose, Hector Cajigas: Nothing to Disclose, Charles Burger: INSMED: Consultant, GossamerBio: Consultant, Janssen: Consultant, John Moss: Nothing to Disclose, Hilary DuBrock: Nothing to Disclose 1309 SERUM AND URINARY METABOLOMICS ARE ASSOCIATED WITH THE DEVELOPMENT OF DE NOVO METABOLIC SYNDROME AFTER LIVER TRANSPLANT: A MULTI-CENTER LONGITUDINAL STUDY Jasmohan Bajaj 1 Isobel Jane Cox 2 Mette Munk Lauridsen 1 Adrien Le Guennec 3 Andrew Fagan 4 Geena George 5 Amy Bartels 1 Thresiamma Lukose 5 Elizabeth Verna 5 , 1 Virginia Commonwealth University, 2 Roger Williams Institute for Hepatology, 3 Kings College London, 4 Richmond VA Medical Center, 5 Columbia University Medical Center Background: Liver transplantation (LT) is associated with development of de novo metabolic syndrome (MetS) and adverse cardiovascular events over time
Il est utilis dans le traitement et la prvention de la carence en vitamine B12 chez les patients prsentant des affections telles que :_ Anmie addisonienne (prareuse) Malabsorption Gastrite atrophique Traitement prolong avec la metformine La prolifration bactrienne de l'intestin grle (SIBO) gastrectomie totale ou partielle Infection par le parasite poisson Diphyllobothrium latum infection Helicobacter pylori Dysfonction pancratique Cancer du pancras ou des intestins Carence alimentaire (par exemple, mauvaise nutrition ou rgime vgtalien) Dficience en transcobalamine II Il est galement utilis dans le cadre du test d'absorption de la vitamine B12 (test de Schilling)
Dysbiosis of oral microbiota, which could damage the epithelial barrier, activate immune responses, and stimulate submucosal cells, may be related to the progression and malignant transformation of OSF
