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The cotton leaves showed no symptoms at 0-6 dpi but became chlorotic, necrotic and defoliated at 12-18 dpi upon inoculation with V991 (Supplementary Fig

These findings provide novel insights for precision medicine approaches in SLE management, particularly for refractory cases that respond poorly to conventional therapies

The heatmaps were generated by loading the data in R-studio version 2023.03.0, rows were normalized, and Euclidian distances were calculated using the pHeatmap package 1.0.12

Breakouts, redness, and irritation (particularly in sensitive or acne-prone skin types) can result from over-stimulation of the skin barrier