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During oxidative stress, NRF2 monitors the cellular response to oxidative stress by mediating detoxification through dissociation from the cytoplasmic inhibitor Keap1, which then translocates to the nucleus and activates the NRF2 transcriptional gene to provide cellular protection against oxidative stress (Hayes and McMahon, 2009)

Antioxidants , 12 , 814 (2023)

These can include Cushings syndrome, adrenal fatigue, high blood sugar, hypertension, and growth retardation in children

NAC may effectively reduce cardiac iron level, exert antioxidant and anti-inflammatory effects, improving cardiac and cognitive functions (Sumneang et al., 2019)