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It may also mitigate some side effects of chemotherapy drugs and be useful in treating cachexia, a condition characterized by severe muscle and weight loss, often associated with cancer 2

TrxR1 forms these inactive cross-linked dimers due to oxidation at Trp114 in the dimer-dimer interface (Xu et al., 2015)

GHK-Cu generally shows better thermal stability in aqueous solutions, while AHK-Cu may require antioxidant systems for long-term formulation stability