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52 Inhibiting cystine import through system Xc induces ferroptosis, an iron-dependent, lipid peroxidation-mediated form of RCD, highlighting the importance of this antiporter in maintaining cellular GSH levels and redox balance 53 (Figure 2)

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Extending human primary cell culture approaches 1,42,43 , we targeted TFs in a homogeneous RG population and then removed growth factors to permit cortical neurogenesis, cell fate choice and early subtype specification