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Cell 8 , 727738 (2005)

40 (19), e108863

and Bell, D

While we cannot rule out that the differences in the conformation of the middle loop may come from crystal packing constraints or the allosteric effects from binding to GPCRs 24,25,26,27 , it is tempting to speculate that the larger conformational changes in -strand V upon Src SH3 binding might affect the coupling of arr1 to the receptor and the downstream signaling