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Unlike oral medications that increase blood flow to the genital area, PT-141 acts on the central nervous system by activating melanocortin receptors, which play a key role in sexual arousal and desire

Reccurent disease can be treated with repeated metastectomy.[81-83] Ollila et al points out that prolonged disease-free interval prior to recurrence and complete surgical metastasectomy of the recurrence were the two most important prognostic factors for survival after recurrence

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