Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan fluorescent Product Name Lenalidomide-CO-PEG6-C2-Cl Synonyms Lenalidomide-4'-CO-PEG6-C2-Cl

Product Name Lenalidomide-CO-PEG6-C2-Cl Synonyms Lenalidomide-4'-CO-PEG6-C2-Cl CAS Number n/a Related CAS Molecular Formula C28H40ClN3O10 Molecular Weight 614

509–514 (2020)

Product Name Sulfo-CA-SiR Synonyms Sulfo-CA-SiR650 CAS Number N/A Related CAS N/A Molecular Formula C40H53ClN3O8SSi Molecular Weight 799

58 SMILES [N-]=[N+]=NCCOCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan fluorescent Product Name Lenalidomide-CO-PEG6-C2-Cl Synonyms Lenalidomide-4'-CO-PEG6-C2-ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by