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This decline correlates directly with reduced collagen production, slower wound healing, increased inflammation, and the visible signs of skin aging wrinkles, sagging, dullness, and loss of elasticity

mtDNA repair methods include base excision repair, mismatch repair, single-strand break repair, double-strand break repair, and homologous recombination

Soluble Uric Acid Triggers the NLRP3 Inflammasome in a Mitochondrial ROS-Dependent Manner In an attempt to address the mechanisms by which sUA promotes NLRP3 inflammasome activation, we analyzed mitochondrial ROS production by staining cells with the mitochondrial-targeting fluorescent probe MitoSOX 53

NFS2 is a group II Cys desulfurase (Mihara et al., 1997