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465,466 Nevertheless, CRS and ICANS have emerged as significant obstacles impeding the broader application of CAR-T cell therapy in cancer treatment, marked by hyperactivation of the immune system and elevated levels of serum cytokines and pro-inflammatory molecules linked to the proliferation of CAR-T cells (Table 5)

Studies indicate that fiber intake can reduce the risk of COPD due its anti-inflammatory effect, since systemic inflammation is an important feature of COPD (147)

Ultimately, it seems as though injury to the NMJ is a culmination of mutant protein aggregation at the presynaptic nerve terminal, presynaptic cholinergic dysfunction, impaired axonal transport, reduced synaptic acetylcholinesterase, and diseased muscle itself, among others [292]

3.11 Neuroprotective efficacy of GO@GSH-FA on neuronal injury post-ischemia-reperfusion To elucidate the neuroprotective potential of GO@GSH-FA, we performed both histological and molecular analyses on cerebral ischemia-reperfusion injury lesions