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One of the ways to tell if B12 deficency (rather than folate deficiency) is the problem is if any of your symptoms (even tiredness) return before the next injection is due...then improve once you've had an injection

While mild increases in ROS can be conducive to normal cellular functioning by activating the phosphatidyl inositol 3 kinase (PI3K) and mitogen activated-protein kinase (MAPK)/extracellular-regulated kinase 1/2 (ERK1/2) growth signaling, excessive ROS can lead to cell stress and oxidative damage to important macromolecules, ultimately leading to cell death (81, 82)

10.3389/fendo.2025.1618984 94 WangX.HuangY.YangY.TianX.JinY.JiangW.et al (2025)

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