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In a randomised clinical trial involving five treatment arms with doses of between 2.5 g/day and 1000 g/day, Eussen [33] concluded that a dose of at least 600 g/day was required to obtain adequate results

Once reconstituted, they should be kept refrigerated at 2C to 8C and used within the recommended timeframe

Pinealon protection against NMDA excitotoxicity is particularly relevant to stroke

Additional considerations include an evolving understanding of drug-induced SCLE (DI-SCLE), the potential for biomarker-driven therapy, targeted use of novel interventions (eg, Janus kinase [JAK] inhibitors), and complications such as calcinosis cutis