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Drug Delivery Rev 2013, 65, 3648

On the other hand, it remains unclear whether SLC7A11 high or SLC7A11 low tumors should be selected for SLC7A11 inhibitor treatment

doi: 10.1016/j.bja.2019.03.006

Se is toxic to cancer cells due to a correlated action between its pro-oxidant activity and its ability to generate reactive oxygen species (ROS), which leads to apoptosis (Gandin et al., 2018)