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Prolonged homeostatic disruption impairs protein degradation processes, weakens molecular chaperone capacity, fosters inflammation, and incites mitochondrial damage through ROS/Ca 2+ , potentially affecting the follicular microenvironment and oocyte developmental potential [332, 333]

Blue crab shells, in addition to containing chitin and chitosan, are rich in carotenoids, particularly astaxanthin, a potent antioxidant with well-documented anti-inflammatory and health-promoting properties

Single LC-MS is limitedas compared to tandem MSby a lower selectivity, as it measures only the molecular ion using selected ion monitoring (SIM)

Elevated homocysteine levels have been consistently associated with an increased risk of cognitive decline, cardiovascular disease (especially stroke), and early mortality