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In addition, the integration of explainability techniques provides insight into the most influential features driving model decisions, thereby improving the interpretability of results and confidence in the adoption of classification tools by clinicians

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These factors may determine abnormal signaling to neural circuits (intrinsic primary afferent nerves and extrinsic primary afferent nerves), which in turn may affect intestinal physiology and sensory perception (197)

Weight and anthropometric outcomes Percentage weight loss The average percentage weight-loss trajectories with semaglutide and placebo over 4 years of observation are shown in Fig