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1 Introduction Autoimmune disorders represent a prominent class of pathologies defined by a breakdown in self-tolerance, where a dysregulated immune system attacks host tissues, thereby initiating localized or systemic inflammatory damages ( 2 Mechanism of ferroptosis Ferroptosis, a term coined by Dixon et al

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Glutathione metabolism reprogramming is associated with immune suppression and an increased proportion of exhausted T cells in the tumor microenvironment