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Otto Warburg first reported that in cancer cells, glycolysis predominates under aerobic conditions, while in normal cells, mitochondrial metabolism is favored in the presence of oxygen [20, 21]

H., Liedorp, P

Nutrients, 10 (12), 1892

This review provides a comprehensive analysis of the mechanisms driving innate immune activation in vitiligo, with a particular focus on damage-associated molecular patterns (DAMPs), oxidative stress, and key innate immune cells, including dendritic cells (DCs), natural killer (NK) cells, and innate lymphoid cells (ILCs), and their crucial role in bridging innate and adaptive immunity