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Description

Retarding physical- and chemical degradation of the polypeptide chains, these favorable biophysical properties have been exploited in pharmaceutical formulations to increase the shelf-life of insulin products

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They remain damaged, inactive, and potentially immunogenic

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Cardiorenal Med 8(4):321331 Kataoka Y et al (2014) Myeloperoxidase levels predict accelerated progression of coronary atherosclerosis in diabetic patients: insights from intravascular ultrasound

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The freezing process may cause some discomfort or pain, but it is generally well-tolerated

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