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One patient with the combination of del(17p) and chromosome 12 trisomy had an abnormally high level of mitochondrial superoxide after AZD-5991 and ibrutinib treatment (a 551-fold increase while on ibrutinib alone and a 74-fold increase while on combination treatment with ibrutinib and CB-839

In addition to ferroptosis inhibitors, other drugs can exert both antiferroptotic and anti-fibrotic effects

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Children diagnosed with autism display elevated lipid peroxidation levels, notable antioxidant serum proteins, modified glutathione levels, and crucial antioxidant enzymes, including glutathione peroxidase, superoxide dismutase, and catalase [115]