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However, careful consideration is warranted when employing GPX4 inhibitors and ferroptosis inducers in AML and other cancer types, as the tumor microenvironment significantly influences tumor progression, either by promoting or inhibiting it

These involve cholinesterase enzyme inhibitors (natural, synthetic, and hybrids) and N-methyl D-aspartate (NMDA) antagonists

the prophylactic or therapeutic agents may be formulated with suitable polymeric or hydrophobic materials (for example as an emulsion in an acceptable oil) or ion exchange resins, or as sparingly soluble derivatives, for example, as a sparingly soluble salt

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