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We also note that in section II.M

"Theyre typically synthetic compounds manufactured outside FDA oversight, often by compounding pharmacies, and administered at doses far exceeding what the body would naturally produce," Ring said

The data discussed here summarize some of the roles of endogenous estrogens, estrogen-based therapies, and estrogen-like molecules on brain homeostasis, particularly in neurogenesis, gliogenesis, and regulation of the neuroprotection/neurodegeneration balance

The laboratory of Frank Giblin has been instrumental in establishing the significance of the glutathione redox cycle in protecting the lens from oxidative damage (Fig