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Taliaferro, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Collectively, our findings demonstrate that MAT2A promotes SRF SUMOylation, thereby increasing its protein stability and nuclear retention, which in turn enhances SRF-dependent transcriptional activation of PARN

Furthermore, a substantial reduction was observed in the hepatic lipid content of rodents (157)