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It is a synthetic analog of human growth hormone (HGH), originating from the modification of the growth hormones last 16 amino acids at positions 176 to 191

The containers are sealed immediately after filling to ensure that the contents remain sterile

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In contrast, intercurrent events such as smoking cessation or switching to another approved weight-loss medication would only need to be accounted for in trials in which these phenomena are expected to have a substantial effect on the endpoint in question, for example, if the intercurrent event is common, or if it occurs at different rates between active and placebo arms