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In female rats, trauma led to reduced abundance of Bifidobacterium, Clostridium sensu stricto, Turicibacter , and Barnesiella genera some of which are involved in short-chain fatty acid (SCFA) production and serotonergic ( Turicibacter ) regulation (Laudani et al., 2023

22 Moghimi et al also reported that deceased COVID-19 patients had lower glutathione (GSH) levels and increased reactive oxygen species (ROS) production in their cell nuclei compared to healthy controls

Therefore, it lacks positional information for hydroxylation and glucuronide conjugation

however, they reported that preliminary studies from their laboratory using inhaled NAC did not see any protective effects against DEPs in an in vivo human nasal model [53]