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While iron chelators can reduce iron load-related injury in animal models, in clinical application, attention must be paid to potential systemic side effects of long-term systemic iron chelation therapy, such as anemia, immune disorders, and metabolic abnormalities

3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)

[11] Women from South Asian backgrounds show higher rates of B12 deficiency in UK populations and may benefit from assessment

The Appropriate Conclusion The existence of limited human reports means BPC-157 is not entirely absent from human literature