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Hemolysis of erythrocytes has long been recognized as a key storage-induced lesion [225]

Within these populations are people with risk factors that might make them better candidates than others, such as: Stress: Chronic stress not only promotes an inflammatory state but also can prolong bacterial infections and discourage wound closure.7 21 22 Overweight or obesity: People with excess weight are also at risk for chronic inflammation, persistent infections, and slower wound healing