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found that H3K18 lactylation positively regulates the transcription of CD39, CD73, and chemokine (C-C motif) receptor 8 (CCR8) to increase the proportion of Tregs, dampening immune activity

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the control only reached 35 % When they blocked VEGFR2 (with the selective inhibitor SU5416), all of these effects disappeared Why it matters: The last point is what holds the study together