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Exposure of the nematode Aphelenchus avenae to low concentrations of 1,2-dibromoethane resulted in a very small conversion of the halide just before death

However, contrasting results have also been reported documenting no changes in the Firmicutes/Bacteroidetes ratio in gut microbiota of rats and mice exposed to AgNPs at dose levels of 9 mg/kg bw/day and 10 mg/kg bw/day, respectively (Wilding et al., 2016

The abbreviations for reduced proteins are rBcp1, rC45S, and rC50S in the manuscript

According to the company and consistent with published pre-clinical literature, it has been studied in animal models for pre-clinical signals related to the gastrointestinal environment, inflammatory responses in the GI tract, and tissue-related processes in tendon and joint contexts - all per pre-clinical animal data, not established human clinical outcomes