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Central compartment recurrence: diagnosis and surgical strategy

Once absorbed, isothiocyanates, such as glucoraphanin-derived sulforaphane, are conjugated to glutathione in the liver, and then sequentially metabolized in the mercapturic acid pathway ( Figure 3 )

Moreover, intracellular GSH buffered NO production at the post-translational level and participates in protecting monocytes from their own oxidative stress without abrogating NO production and endosome acidification

Thus, GSH reduces the pro-viral DNA load in the first period of infection, suggesting that this antioxidant may be useful for improving current antiviral therapies (Palamara et al., 1996)