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In the TASCC, autophagy degrades proteins into small molecules, such as amino acids, and these amino acids activate mTOR to induce the synthesis of various cytokines, chemokines, etc

The TRPV1 channel has been described in the acrosome and flagellum of bull spermatozoa, where it promotes progressive motility, capacitation, including hyperactivity, and acrosome reaction (67)

Furthermore, lipid metabolic reprogramming in HCC leads to elevated serum angiopoietin-like protein 6, which effectively distinguishes non-malignant HBV patients from alpha-fetoproteinnormal individuals with early HBV-associated HCC [460]

Historical records in traditional Chinese medicine document the use of feces to treat illnesses, dating back approximately 1,700 years when Ge Hong used human fecal infusions to treat patients on the brink of death due to food poisoning, diarrhea, and fever