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Abstract Opioid receptors (OR) are part of the class A of G-protein coupled receptors and the target of the opiates, the most powerful analgesic molecules used in clinic

For example, biejia extract could inhibit PI3K/Akt/mTOR signaling in MDA-MB-231 breast cancer cells, attenuating EMT and metastatic behaviors (Yang et al., 2022)

Emerging evidence has shown that Oxidative stress (OS) plays a key mediator in the development of obesity and its complications