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Since, the juvenile worms of Isoparorchis hypselobagri penetrate the intestine, liver and swim bladder before transforming into an adult stage, we hypothesise that the migrating juvenile worms cause tissue damage that could result in the down-regulation of antioxidant enzymes

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The generation of reactive oxygen species (ROS) in response to a 2h-palmitate treatment was measured using MitoSOX dye