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10.1016/j.cmet.2013.12.017 69 LiD

This article is the first to have drawn attention to the possible role of brain hypoxia in migraine pathogenesis

In eukaryotic cells, the overall amino acid substitution rate for m 1 -modified luciferase was reported at approximately 0.8%, with phenylalanine being replaced by serine, isoleucine, or leucine a rate slightly higher than that of unmodified mRNA but varying across specific codons [200]

This systemic inflammatory response triggers peripheral vasodilation and increased capillary permeability, leading to the patient's hypotension and compensatory tachycardia