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Newly differentiated OLs extend their processes and quickly rearrange their membranes to generate internodes around multiple axons through a series of coordinated steps that include: (1) identification and signaling with the target axons, (2) axonal wrapping with membrane outgrowth, (3) transporting membrane components, (4) compacting myelin sheaths, and (5) node establishment (Simons et al., 2024)

In a mouse model of RILI, inhibition of expression of the key factor GPX4 induced ROS accumulation leading to lipid peroxidation, further suggesting that ferroptosis RILI plays an important role

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10.1523/jneurosci.3902-05.2006 78 SunL.LanJ.LiZ.ZengR.ShenY.ZhangT.et al (2024)