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Males consistently demonstrate higher prevalence across all age groups, with the disparity most pronounced between 50 and 70 years of age [40]

Key amino acids, including arginine, proline, and glutamine, contribute to the regulation of fibroblast activity and collagen synthesis, all of which are essential for fibrotic progression

Type 2 inositol 1,4,5-trisphosphate receptor is predominantly involved in agonist-induced Ca(2+) signaling in Bergmann glia

Preclinical investigations have consistently demonstrated that HAGSH scaffolds accelerate wound closure, enhance collagen organization, and promote vascularization across acute and chronic wound models