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Since causal relationships of specific key genes in a metabolic pathway can be cell type-specific and comorbidity-dependent, the impact of cell-specific metabolic changes must be thoroughly explored in vivo , with a focus on also systemic effects

6.3 Crosstalk between the glutathione and thioredoxin systems The glutathione (GSH/GR/GPx) and thioredoxin (Trx/TrxR/Prx) systems constitute the two primary thiol-based antioxidant defenses in cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Tasoglu S., Demirci U., Demirci U

2018, doi:10.17179/excli2018-1092 24.Hernndez Bautista RJ, Mahmoud AM, Knigsberg M, Lpez Daz Guerrero NE