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This results in decreased expression of the articulin CD2AP and the podocyte cytoskeleton protein synaptopodin, while increased expression of the transcription factor snail and nerphrin, a marker protein of podocyte injury, ultimately leads to podocyte actin skeleton remodeling and cell migration[94]

10.11648/j.ijpc.20170306.12 96 KhanM

Standardized root extract of Withania somnifera and withanolide A exert moderate vasorelaxant effect in the rat aortic rings by enhancing nitric oxide generation