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Recon3D: a resource enabling a three-dimensional view of gene variation in Human metabolism

For example, Zerin et al

In this study in rats, low doses of withaferin A were shown to have a cardioprotective effect by upregulating the mitochondrial anti-apoptotic pathway due to an increase in AMP-activated protein kinase (AMPK) phosphorylation and an increase in the Bcl-2/Bax ratio (AMPK) [54]