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It is based on clinical protocols used by licensed healthcare professionals

Androgen receptor in human endothelial cells

in Pharmaceuticals (Basel) (2025, PMID: 40005999)

But only a maximum of 5mcg of B12 enters the bile every day (according to "Advanced Haematology" 7th edition textbook, page 60), so it seems that only an additional 5mcg would be lost daily if none was recovered