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Bellinger FP, Bellinger MT, Seale LA, Takemoto AS, Raman AV, Miki T et al

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NAPstars1, 2, 3, 6 and 7 exhibited pronounced NADPH-dependent changes in TS fluorescence excitation and emission spectra, with excitation and emission maxima at approximately 400 and 515 nm, respectively, and with a spectroscopic dynamic range of approximately 2.5, i.e

This indicated that the TrxR1/Gsr-null livers excrete much more oxidized GSSG than do wild type livers, which likely is critical for sustaining the reduced state of the intracellular [GSH/GSSG] redox couple in the absence of GSSG-reductase activity [107]