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To elucidate the molecular origin of the 5-nitroimidazole ether activity switch, we solved high-resolution X-ray structures of monomeric HpTpx and in complex with both ligands (see Supplementary Section 1 for detailed structural information)

Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1

I2 and I3, two new EN460 analogs with different phenyl-substituted moieties, efficiently inhibited ERO1A, blunting VEGFA secretion

Medicine Side Effect Some antibiotics, such as tetracycline, are likely to cause teeth discoloration, especially in children whose teeth are still developing