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[1] [3] The standard UK treatment involves hydroxocobalamin 1mg intramuscular injections, with dosing regimens typically consisting of initial loading doses (e.g., every other day for two weeks) followed by maintenance doses every 2-3 months for conditions like pernicious anaemia

Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene

Protein crystal structures were obtained from the RCSB protein databank (rcsb.org) for ACLY (PDB ID 6POF), ACC (PDB ID 5CSK) and FAS (PDB ID 2VZ8) or UniProt (uniprot.org) for CIC (P53007)