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"Extreme longevity is likely governed not by a single gene, but by coordinated changes across multiple biological systems, including genome stability, iron metabolism, immune function, and stress resistance," he said, adding that the work could inform research on human aging and age-related diseases

In 2010, Quercetin received GRAS approval from the US The Food and Drug Administration (FDA) has approved certain substances in beverages, cereal products, pasta, processed fruits and juices, and gummies, permitting production from natural sources

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Yao J, Pan J, Jiang Q et al (2024b) Baicalein inhibits NLRP3 inflammasome activation and mitigates placental inflammation and oxidative stress in gestational diabetes mellitus