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ROS can directly damage biological structures, including lipids, proteins, and DNA, contributing to cell death, necrosis, and apoptosis (Juan et al., 2021)

Additionally, studies have shown that fatty acids produced by gut microbes, especially unsaturated fatty acids, are closely associated with the inflammatory state of IBD [12, 13]

J Cell Sci 126(9):19051912 Aits S, Kricker J, Liu B, Ellegaard A-M, Hmlist S, Tvingsholm S, Corcelle-Termeau E, Hgh S, Farkas T, Holm Jonassen A (2015) Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay