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10.1152/physrev.00018.2001 24 DuJ.CullenJ

That is why every efficacy statement here is hedged with studied for, in research, or preclinical. It is not lawyerly throat-clearing

Despite the diversity of their structures, most of them share common features, such as an amphipathic character and several charged residues

Shaw et al.(45) described five patients with a relapsing steroid-responsive encephalopathy including episodes like stroke and seizures, high CSF protein, abnormal EEG, and normal CAT scans (see Hashimoto's encephalopathy below)