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Description

Perez-Pinera, P

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Hepatology 74 , 24522466 (2021)

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Impaired GSH synthesis leads to disrupted cell signaling and an increased risk of neurological diseases (Aoyama and Nakaki, 2013)

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Importantly, Akt/PKB also phosphorylates forkhead transcription factors of the FOXO subfamily, and this leads to their inactivation and retention in cytoplasm [254,255] resulting in a reduced transcriptional activity [256]

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