2.5.1 Hesperidin (HD) 2.5.1.1 Effects of HD on hepatic oxidative stress and inflammation The antioxidative effects of HD have been verified in numerous chemical-induced liver injury animal models
Conflict of interest AT was employed by Guangzhou Qingke Biotechnology Co., Ltd
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Disease risk reflects a multifactorial interaction between genetic susceptibility (PARK-associated genes) and environmental neurotoxins, and experimental modeling traditionally relies on neurotoxin-based paradigms (e.g., rotenone, 6-hydroxydopamine (OHDA), 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), and paraquat) or manipulation of PD-linked genes such as SNCA (codifying for -Syn), leucine-rich repeat kinase 2 (LRRK2), PTEN-induced putative kinase 1 (PINK1), parkin RBR E3 ubiquitin protein ligase (PRKN), and parkinsonism associated deglycase-1 (DJ-1) (281283)
